top of page

Prism
Powered by the Brain.

An interventional psychiatry suite of solutions powered by
fMRI-informed digital biomarkers for personalized patient care. 

GrayMatters Health is leading a transformation - bringing evidence-based, accessible technology to psychiatry clinics to augment standard-of-care therapies and help improve patient outcomes and patient lives.

 

With a strong foundation in scientific research, Prism self-neuromodulation is being used in clinical practice to help patients get Back to Better™. This innovation enables patients to learn to regulate brain activity associated with their mental health condition in the clinic, gaining a skill for use in their daily lives.  

 

Prism is a comprehensive suite of solutions for scientifically leveraging the power of the brain, featuring protocols for PTSD and Depression.  

 

PTSD

Patients learn to down-regulate an amygdala-based biomarker to treat symptoms associated
with post-traumatic stress disorder (PTSD).

​

Prism for PTSD effect sizenew.png

Depression

Patients learn to up-regulate the reward-system biomarker (Ventral Striatum based) to help live better with depression. ​​

​

depression graph for web.png

Watch our Prism for PTSD patient animation

Value for your patients and your practice

Leading-edge technology

​

The ground-breaking fMRI-Informed digital biomarkers that power Prism have a strong scientific and clinical foundation. The PTSD protocol uses an amygdala-based biomarker and the Depression protocol uses a reward-system biomarker. Learn more >>

Operational simplicity​

​

Integrates seamlessly with clinic operational flow from intake to treatment. GMH provides onsite installation and training as well as in-person and remote support.​

Personalized care​

​

In real-time, Prism reads the signal from the EEG sensors on the patient’s head and computes the relevant digital biomarker. These signals are the result of mental strategies the patient selects – this is as personal as a treatment can get.

​​​​​​​

​

Keeps costs top of mind

​

Prism sessions can be administered by a technician to optimize clinician time and clinic resources.

 

 

mesh-gradient_edited.jpg

Impact on
Patients

"Since using Prism, my quality of life has improved and my capacity to enjoy life has really opened up! I feel calmer, more in control, and am thinking more clearly.”
Prism Patient​

Sign up for
our newsletter

GrayMatters Health logo

© 2025 GrayMatters Health. All Rights Reserved.

Disclaimer: The information on this website is not intended to be a substitute for professional medical advice. Always discuss treatment options and treatment outcomes with your physician or other qualified mental health provider.​

  • LinkedIn
  • Youtube
bottom of page