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Prism
Powered by the Brain.

An interventional psychiatry suite of treatments and solutions powered by
fMRI-informed digital biomarkers for personalized patient care. 

GrayMatters Health is leading a transformation - bringing evidence-based digital biomarker technology to psychiatry clinics to augment standard-of-care therapies and help improve patient outcomes and patient lives.

 

With a strong foundation in scientific research, Prism self-neuromodulation is being used to help patients learn to regulate brain activity associated with their mental health condition in the clinic, gaining a skill for use in their daily lives.  

 

Prism is a comprehensive suite of solutions for scientifically leveraging the power of the brain, featuring protocols for PTSD and Depression. Learn more >> 

 

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Prism™ Imagine. Selfie of the mind™.

GrayMatters Health introduces a new way to connect with your patients in their daily life. Learn more >>

Leading-edge technology

The ground-breaking fMRI-Informed digital biomarkers that power Prism have a strong scientific and clinical foundation. The PTSD protocol uses an amygdala-based biomarker and the Depression protocol uses a reward-system biomarker. Learn more about our biomarkers >>

Operational simplicity

Prism integrates seamlessly with operational flow from intake to treatment. All you need is a quiet room, table and chair and a trained Prism Operator. Read a Case Study of a Community Clinic in Texas.

Personalized care

At the core of Prism is the mental strategy. Each patient explores which personal memory, emotion or experience gets the animated characters in the Prism simulation to respond. A mental strategy is as personal as it gets!

With you every step of the way

A dedicated Account Manager will be your co-pilot to help build a Prism service at your practice. Ask about our Prism Pathway to guide you.

 

 

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Impact on
Patients

"Since using Prism, my quality of life has improved and my capacity to enjoy life has really opened up! I feel calmer, more in control, and am thinking more clearly.”
Prism Patient

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© 2026 GrayMatters Health. All Rights Reserved.

Disclaimer: The information on this website is not intended to be a substitute for professional medical advice. Always discuss treatment options and treatment outcomes with your physician or other qualified mental health provider.​

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